Bitter Sophora Root Extract
Bitter Sophora Root contains about a dozen alkaloids, with matrine and oxymatrine being by far the highest, together comprising about 2% of the dried root stock (most of it in the form of oxymatrine), followed by closely related alkaloids: mainly sophocarpine, but also minute amounts of sophoranol, sophoramine, sophoridine, allomatrine, isomatrine, and others. These alkaloids were first reported as constituents of kushen in a series of publications from 1958-1978.An overview of recent research on the pharmacology and clinical applications of the sophora alkaloids is presented below. In general, the dosage of the sophora alkaloids administered clinically is in the range of 400-600 mg per day.
Product Name: Bitter Sophora Root Extract
Latin Name: Sophora flavescens
Plant part used: Root
Active Ingredient: Matrine, Oxymatrine
Specification: Matrine 1%,10%,20%,90%,98%
Test Method: HPLC
Extract Method: Grain Alcohol/Water
Appearance: White Fine Powder
Molecular Formula: C15H24N2O
Molecular Weight: 248.36
An alkaloid extracted from the chinese sophora herb plants; has a relatively low toxicity; demonstrated antiviral and anti-inflammatory bioactivity; shows to induce apoptosis in many human cancer cell lines
Molecular Formula: C15H24N2O2
Molecular Weight 264.36
Oxymatrine is a quinolizidine alkaloid extracted from the root of Sophora flavescens, which is used for the treatment of viral hepatitis, cancer, viral myocarditis, gastrointestinal hemorrhage and skin diseases.
Matrine and oxymatrine are the two major alkaloid components found in bitter sophora root. They are obtained primarily from Sophora japonica (kushen), but also from Sophora subprostrata (shandougen), and from the above ground portion of Sophora alopecuroides. An intensive investigation into the pharmacology and clinical applications of these alkaloids has gone on for the past decade and remains one of the focal points of Chinese medical research. The main clinical applications of bitter sophora root extract are treatment of people with cancer, viral hepatitis, cardiac diseases, and skin diseases.
1.Applied in Pharmaceutical as capsules or pills;
2.Applied in Functional food & Health products as capsules or pills;
3.Applied in Food Industry: Water-soluble beverages;
4.Applied in Cosmetics field.