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    • glutathione lighten skin, Glutathione manufacture, Glutathione for cosmetic
    • glutathione lighten skin, Glutathione manufacture, Glutathione for cosmetic
    • glutathione lighten skin, Glutathione manufacture, Glutathione for cosmetic
    • glutathione lighten skin, Glutathione manufacture, Glutathione for cosmetic

    SQT® Lighten Skin 98% L-Glutathione Reduced Powder INCI No.: 02586

    Catalog No: SQT20201201

    View(s): 565

    Product Name: SQT® 98% L-Glutathione Reduced for Cosmetics
    INCI Name: Glutathione
    Color: White
    INCI No.: 02586
    EINECS code: 200-725-4
    CAS: 70-18-8
    HS Code: 2930909099
    Molecular formula: C10H17N3O6S

    Contact Us

    For more product information, please call: +86 155 8088 9901

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    Contact Us

    • Phone

      +86 155 8088 9901

    • E-mail

      info@sunshineextract.com

    • Address

      Bldg. E7, Lugu Yuyuan, High-Tech Development Zone, Changsha, Hunan, China

    Product Details

    What is the Glutathione?

    Glutathione (GSH) is an antioxidant in plants, animals, fungi, and some bacteria and archaea. Glutathione is capable of preventing damage to important cellular components caused by reactive oxygen species such as free radicals, peroxides, lipid peroxides, and heavy metals. It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and cysteine. The carboxyl group of the cysteine residue is attached by normal peptide linkage to glycine.

    L-Glutathione 98%

    CERTIFICATE OF ANALYSIS

    Product Name
    L-Glutathione reduced
    Specification
    98%
    Batch No.
    SQT20201201
    CAS
    70-18-8
    Irradiation
    Free
    GMO
    Free
    BSE
    Free

    Assay
    Limits/Specification
    Test Method
    Results
    PHYSICAL-CHEMICAL ANALYSIS
    Identification
    Complies
    HPLC
    Complies
    Assay 
    98.0%~101.0%
    HPLC
    98.33%
    Appearance
    White or kind of white powder
    Organoleptic
    Complies
    Colour
    White or kind of white
    Organoleptic
    Complies
    Odor
    Characteristic
    Organoleptic
    Complies
    Loss on drying
    NMT 0.5 %
    GB 5009.4-2016
    0.19%
    Specific rotation
    -15.5°~-17.5°
    RT
    -16.0°
    Chlorides
    Not more than 200 ppm
    CP 2015
    Conforms
    Sulfates
    Not more than 300 ppm
    CP 2015
    Conforms
    Ammonium
    Not more than 200 ppm
    CP 2015
    Conforms
    Heavy metals(Pb)
    Not more than10ppm
    CP 2015
    Conforms
    Arsenic(As)
    NMT 2ppm
    CP 2015
    Complies
    Iron
    Not more than 10 ppm
    CP 2015
    Conforms
    Residue on ignition
    Not more than 0.1%
    CP 2015
    0.03%
    Related substances
    (gross contamination)≤2.0%
    CP 2015
    1.62%
    (GSSG)≤1.5 %
    CP 2015
    0.82%
    MICROBIOLOGICAL TESTS
    Total Bacterial Count
    <1000 cfu/g
    GB 4789.2-2016
    Complies
    Total Molds Count
    <100 cfu/g
    GB 4789.15-2016
    Complies
    Staphylococcus aureus
    Negative
    GB 4789.10-2016
    Negative
    E.Coli  
    Negative
    GB 4789.3-2016
    Negative
    Salmonella 
    Negative
    GB 4789.4-2016
    Negative

    The Principes of GSH for human


    Glutathione is a tripeptide (cysteine, glycine, and glutamic acid) found in surprisingly high levels—5 millimolar—concentrations in most cells.

    Glutathione exists in cells in 2 states: reduced (GSH) and oxidized (GSSG). As can be seen in Figure, oxidized glutathione is actually 2 reduced glutathiones bound together at the sulfur atoms.

    Principes of GSH

    Balance Between GSH and GSSG

    GSH is made available in cells in 3 ways

    GSH is made available in cells in 3 ways

    GSH is made available in cells in 3 ways:
    1. De novo synthesis via a 2-step process catalyzed by the enzymes glutamate cysteine ligase (GCL) and glutathione synthetase (requires ATP).
    2. Regeneration of oxidized GSSG to reduced GSH by glutathione reductase (requires NADPH).
    3. Recycling of cysteine from conjugated glutathione via GGTP (requires NADPH).



    The benefits of Glutathione for human


    l-glutathion benifits for human


        Glutathione can directly inhibit the activity of tyrosinase, at the same time it can sweep away a large number of oxidative free radicals, prevent free radicals from activating tyrosinase, and can also be hydrolyzed into cysteine, which interferes with the synthesis of melanin. In other words, in the whitening process, it has the dual effects of "antioxidant" + "inhibition" at the same time.
        Glutathione is also a small peptide with a molecular weight of 307 daltons (molecules greater than 500 daltons cannot cross the skin barrier). This means that the glutathione applied on the skin can be absorbed by the skin. Moreover, it is also an antioxidant component in human cells, which is easier to "pass through" the defense layer and enter the human body more easily.