Hydrolyzed Sponge Technology: Dual Breakthrough in Safety (No Residue) and High-Efficiency Penetration Enhancement
As a key ingredient in the beauty and skincare industry, the safety and functionality of hydrolyzed sponges have always been a major focus. As a professional hydrolyzed sponge manufacturer, our company has conducted two critical experiments on residue safety and high-efficiency penetration enhancement, aiming to validate the reliability and advantages of our products through scientific data. This not only provides important evidence for clinical applications but also establishes a high-standard product evaluation system for the industry.
Safety with No Residue: Microscopic Observation Confirms Hydrolysis Properties
Key experimental data revealed: Microscopic photo evaluation confirmed that 6 hours after application, the hydrolyzed sponge microneedles had completely dissolved and cleared from the ex vivo model (porcine skin). Under laboratory conditions, this hydrolyzed sponge product posed no residue risk after 6 hours of proper use. This result proves that our hydrolyzed sponge leaves no residues on the skin surface, eliminating potential safety concerns.
As a professional hydrolyzed sponge manufacturer, our company has verified the safety performance of our products through rigorous laboratory studies. Using an ex vivo porcine skin model, we observed the morphological changes of hydrolyzed sponge residues under a microscope system. Experimental data showed that after 6 hours of proper use, no sponge residues were visible under the microscope, and the microneedles had completely dissolved and been expelled from the porcine skin surface.
High-Efficiency Carrier Function: Vitamin C Sustained Release and Transdermal Promotion Study
Comparative experiments showed:
For non-hydrolyzed sponge-loaded vitamin C, the transdermal absorption rates at 4h and 16h were 0.015% and 0.022%, respectively, with no interference from the blank solution on the main peak.
When adding hydrolyzed sponge microneedle content as specified in the officially listed cosmetic raw material directory, the transdermal absorption rates at 4h and 16h were 1.01% and 1.50%, respectively, with no interference from the blank solution. Compared to non-loaded vitamin C, the penetration enhancement multiples were 67.33x and 68.18x, respectively.
When adding hydrolyzed sponge microneedle content as per our company’s cosmetic raw material safety evaluation standards, the transdermal absorption rates at 4h and 16h were 1.52% and 1.96%, respectively, with no interference from the blank solution. Compared to non-loaded vitamin C, the penetration enhancement multiples were 101.33x and 89.09x, respectively.
These two studies validate the dual advantages of our hydrolyzed sponge products from different perspectives: ensuring post-use safety with no residues while significantly improving the delivery efficiency of active ingredients as a drug carrier. These properties make it highly applicable in wound care, drug delivery, and aesthetic medicine.
As a leading hydrolyzed sponge manufacturer in the industry, we remain committed to enhancing product purity and quality. Through strict quality control systems and continuously optimized production processes, we ensure that every batch meets the highest standards. In the future, we will continue to advance hydrolyzed sponge technology, exploring its potential in delivering more active ingredients, and providing safer, more reliable, and high-quality products for the beauty and skincare industry.
To further evaluate the performance of hydrolyzed sponges as carriers for active ingredients, we conducted a comparative experiment on the transdermal absorption of vitamin C. By measuring transdermal data at different time points (0h, 4h, 16h) for vitamin C standard solution versus sponge-loaded vitamin C, we validated the sustained-release effect and penetration-enhancing capability of hydrolyzed sponges.
